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Genetic abnormalities may cause cerebral palsy, study suggests

23:01 27-01-2012; source: www.sciencedaily.com

For years it was thought that a difficult birth and other perinatal factors were the leading causes of cerebral palsy (CP), a group of disorders that can involve brain and nervous system functions such as movement, learning, hearing, seeing and thinking. Now, researchers suggest that the majority of cerebral palsy causes may in fact be caused by genetic abnormalities.

Genetic variation that raises risk of serious complication linked to osteoporosis drugs identified

23:01 27-01-2012; source: www.sciencedaily.com

Researchers have identified a genetic variation that raises the risk of developing serious necrotic jaw bone lesions in patients who take bisphosphonates, a common class of osteoclastic inhibitors.

How cholera bacterium gains a foothold in the gut

23:01 27-01-2012; source: www.sciencedaily.com

Biologists have made an important advance in our understanding of the way cholera attacks the body. The discovery could help scientists target treatments for the globally significant intestinal disease which kills more than 100,000 people every year.

Research on vitamins could lead to the design of novel drugs to combat malaria

23:01 27-01-2012; source: www.sciencedaily.com

New research could lead to the design of more effective drugs to combat malaria. The research will enable scientists to learn more about the nature of the enzymes required for vitamin biosynthesis by the malaria causing pathogen Plasmodium. Vitamins are essential nutrients required in small amounts, the lack of which leads to deficiencies. Many pathogenic microorganisms produce vitamins, and these biosynthetic pathways may provide suitable targets for development of new drugs.

Silk from tasar silkworm used as scaffold for heart tissue

22:01 27-01-2012; source: www.sciencedaily.com

Damaged human heart muscle cannot be regenerated. Scar tissue grows in place of the damaged muscle cells. Scientists are seeking to restore complete cardiac function with the help of artificial cardiac tissue. They have succeeded in loading cardiac muscle cells onto a three-dimensional scaffold, created using the silk produced by a tropical silkworm.

Discovery of new vaccine approach for treatment of cancer

22:01 27-01-2012; source: www.sciencedaily.com

Scientists have developed a new vaccine to treat cancer at the pre-clinical level. They developed a new approach for treating the disease based on manipulating the immune response to malignant tumors.